Sorbinil pharmacokinetics in male and female elderly volunteers.
نویسندگان
چکیده
Sorbinil pharmacokinetics were studied, following a single oral dose, in eight male and eight female healthy, elderly volunteers. Elimination half-life tended to be longer in males than in females. There was no sex difference in AUC or renal clearance. The long elimination half-life of sorbinil in the elderly suggests that accumulation is likely to occur with chronic dosing.
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ورودعنوان ژورنال:
- British journal of clinical pharmacology
دوره 23 4 شماره
صفحات -
تاریخ انتشار 1987